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While e-cigarettes do not contain tobacco, they do have the addictive substance nicotine, and are marketed in a variety of flavors that critics say appeal to children and teens

E-liquids are available in a variety of strengths, measured in milligrams per millilitre (mg/ml) often shortened to just mg'

Clonidine is limited by its adverse effect profile, which includes postural hypotension, extreme drowsiness, fatigue, and dry mouth [37]

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